{"id":698,"date":"2023-09-08T19:53:04","date_gmt":"2023-09-08T19:53:04","guid":{"rendered":"https:\/\/www.immersionhealthpdx.com\/?p=698"},"modified":"2023-09-22T22:05:53","modified_gmt":"2023-09-22T22:05:53","slug":"methylation-evaluation-package-its-more-than-just-mthfr","status":"publish","type":"post","link":"https:\/\/www.immersionhealthpdx.com\/methylation-evaluation-package-its-more-than-just-mthfr\/","title":{"rendered":"Methylation Evaluation Package: It&#8217;s more than just MTHFR"},"content":{"rendered":"[vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text]\n<h5>How efficiently do you metabolize hormones, break down environmental toxins, and break down neurotransmitters?<\/h5>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;padding-1-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; advanced_gradient_angle=&#8221;0&#8243; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; gradient_type=&#8221;default&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Methylation is a complex set of biochemical reactions taking place millions of times each second in our cells. And while the details around these reactions are very challenging to understand even with years of study, many people have been told by practitioners they\u2019ve consulted that they are \u201cpoor methylators\u201d based on the status of one particular now-famous gene: methyltetrahydrofolate, commonly known as MTHFR.<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; bg_image=&#8221;670&#8243; bg_position=&#8221;center center&#8221; background_image_loading=&#8221;default&#8221; bg_repeat=&#8221;no-repeat&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;light&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; color_overlay=&#8221;#000000&#8243; advanced_gradient_angle=&#8221;0&#8243; overlay_strength=&#8221;0.5&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221; parallax_bg=&#8221;true&#8221; parallax_bg_speed=&#8221;fast&#8221; gradient_type=&#8221;default&#8221; shape_type=&#8221;&#8221;][vc_column column_padding=&#8221;padding-5-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; advanced_gradient_angle=&#8221;0&#8243; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.5&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; gradient_type=&#8221;default&#8221; column_padding_type=&#8221;default&#8221;][vc_column_text]\n<h3><span style=\"font-weight: 400;\">A few roles that methylation plays in the body:<\/span><\/h3>\n<ul>\n<li>\n<h4><span style=\"font-weight: 400;\">Hormone (especially estrogen) production, metabolism, and detoxification<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"font-weight: 400;\">Neurotransmitter metabolism (and thus stress\/mood regulation)<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"font-weight: 400;\">DNA regulation and cancer protection<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"font-weight: 400;\">Immune cell activation<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"font-weight: 400;\">Detoxification of environmental toxicants including heavy metals and others<\/span><\/h4>\n<\/li>\n<li>\n<h4><span style=\"font-weight: 400;\">Blood pressure regulation<\/span><\/h4>\n<\/li>\n<\/ul>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;padding-1-percent&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; advanced_gradient_angle=&#8221;0&#8243; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221; gradient_type=&#8221;default&#8221;][vc_column_text]<span style=\"font-weight: 400;\">A whole industry has grown up around the treatment of polymorphisms in the MTHFR gene. And there are studies to show that there is an association between some of those polymorphisms and various disease risks. But the fact is, knowing your MTHFR status can\u2019t tell you how efficiently you carry out methylation, any more than knowing the plays in a football playbook can tell you the outcome of a game. The game has to be played in the real world, and the genes have to be expressed and regulated in real cells.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Genes are one thing; gene <\/span><b><i>products<\/i><\/b><span style=\"font-weight: 400;\"> are another. To use another analogy, knowing about polymorphisms \u2013 even lots of them \u2013 is like having the blueprint of a car engine. But you can&#8217;t know how efficiently that engine runs until you actually sample the exhaust of the engine while it&#8217;s running.<\/span>[\/vc_column_text][image_with_animation image_url=&#8221;705&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;center&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][vc_column_text]<span style=\"font-weight: 400;\">This is a <\/span><i><span style=\"font-weight: 400;\">highly simplified <\/span><\/i><span style=\"font-weight: 400;\">depiction of the genes, cofactors, and pathways involved in the methylation cycle. As you can see, MTHFR (depicted in a box in the lower left of this image) is only one gene in a network of many genes involved in supplying the products that run the methylation cycle. If you want to know if you are a \u201cpoor methylator,\u201d you need to know more than the polymorphisms on these genes. You need to know the levels of these gene <\/span><i><span style=\"font-weight: 400;\">products <\/span><\/i><span style=\"font-weight: 400;\">and their <\/span><i><span style=\"font-weight: 400;\">ratios<\/span><\/i><span style=\"font-weight: 400;\">. That tells you if the MTHFR or other polymorphisms are having an actual impact on your methylation cycle.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">I have put together an assess\/test\/review package that will allow you to see not only if you are carrying out cellular methylation efficiently, but also see the health impact impaired methylation might be having.<\/span>[\/vc_column_text][vc_column_text]\n<div>\n<h2>Assessment<\/h2>\n<p><span style=\"font-weight: 400;\">The Nutritional Assessment Questionnaire (NAQ) is among the most comprehensive assessments available for correlating your complete symptom inventory with your personal pattern of eating. The NAQ takes your answers to over 300 questions about your health and your diet and uncovers specific nutrients or food types that are likely to be contributing to your symptoms and underlying organ imbalances. You will receive a link to fill out the NAQ online. Once completed you will then be scheduled for a 45 minute session with Maria, who will go over the results and will make specific recommendations for you regarding dietary adjustments and\/or other therapies that are indicated.<\/span><\/p>\n<h2><span style=\"font-weight: 400;\">Test<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Those purchasing this package will receive a test kit from Genova, one of the largest functional testing laboratories in the country. Their Methylation Panel tests the level of the various methylation cycle reaction products. These are the products that tell us if you are actually spinning that cycle at the speed you need to in order to generate methyl groups. The test quantifies each of the following:<\/span><\/p>\n<\/div>\n[\/vc_column_text]<div class=\"nectar-fancy-ul\" data-list-icon=\"icon-salient-thin-line\" data-animation=\"false\" data-animation-delay=\"0\" data-color=\"extra-color-1\" data-spacing=\"default\" data-alignment=\"left\"> \n<ul>\n<li><span style=\"font-weight: 400;\">Betaine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Betaine\/Choline Ratio<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Choline<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Cystathionine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Cysteine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Dimethylglycine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Glutathione<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Glycine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Homocysteine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Met\/Sulf Ratio<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Methionine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Methylation Balance Ratio<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> SAH<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> SAMe<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> SAMe\/SAH Ratio<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Sarcosine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Serine<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Taurine<\/span><\/li>\n<\/ul>\n <\/div>[\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; column_element_direction_desktop=&#8221;default&#8221; column_element_spacing=&#8221;default&#8221; desktop_text_alignment=&#8221;default&#8221; tablet_text_alignment=&#8221;default&#8221; phone_text_alignment=&#8221;default&#8221; background_color_opacity=&#8221;1&#8243; background_hover_color_opacity=&#8221;1&#8243; column_backdrop_filter=&#8221;none&#8221; column_shadow=&#8221;none&#8221; column_border_radius=&#8221;none&#8221; column_link_target=&#8221;_self&#8221; column_position=&#8221;default&#8221; gradient_direction=&#8221;left_to_right&#8221; overlay_strength=&#8221;0.3&#8243; width=&#8221;1\/1&#8243; tablet_width_inherit=&#8221;default&#8221; animation_type=&#8221;default&#8221; bg_image_animation=&#8221;none&#8221; border_type=&#8221;simple&#8221; column_border_width=&#8221;none&#8221; column_border_style=&#8221;solid&#8221;][image_with_animation image_url=&#8221;719&#8243; image_size=&#8221;full&#8221; animation_type=&#8221;entrance&#8221; animation=&#8221;None&#8221; animation_movement_type=&#8221;transform_y&#8221; hover_animation=&#8221;none&#8221; alignment=&#8221;&#8221; border_radius=&#8221;none&#8221; box_shadow=&#8221;none&#8221; image_loading=&#8221;default&#8221; max_width=&#8221;100%&#8221; max_width_mobile=&#8221;default&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Each component on that test list offers insights into different aspects of the overall methylation process and how efficiently it is working.<\/span>[\/vc_column_text][vc_column_text]\n<h2 style=\"padding-left: 40px;\"><span style=\"font-weight: 400;\">There is a great deal of buzz these days about \u201cpersonalized medicine,\u201d i.e. diet and nutrient recommendations that are based upon every individual\u2019s unique physiology and biochemistry.<\/span><\/h2>\n[\/vc_column_text][vc_column_text]\n<h2><span style=\"font-weight: 400;\">Review<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">With both lab results and the NAQ nutrient analysis in hand, the next component of this package is a 30-minute consultation with me in order to review the labs, determine which (if any) aspects of the methylation cycle are needing the most support, and bring that all together into a coherent and personalized set of recommendations.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There is a great deal of buzz these days about \u201cpersonalized medicine,\u201d i.e. diet and nutrient recommendations that are based upon every individual\u2019s unique genetic makeup. This package takes that two steps further, bringing in physiology and biochemistry, as well as the full nutritional analysis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">This bundle of assessment\/test\/review represents the very definition of personalized medicine.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Bundling tests and services is a way for us to offer discounts. Paid individually, the elements in this package retail at $560. Purchased as a package we\u2019re applying a 10% discount, bringing the total down to $504. Call 503-719-4806 or email <a href=\"mailto:info@immersionhealthpdx.com\">info@immersionhealthpdx.com<\/a> to schedule your complete methylation evaluation.<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=&#8221;in_container&#8221; full_screen_row_position=&#8221;middle&#8221; column_margin=&#8221;default&#8221; column_direction=&#8221;default&#8221; column_direction_tablet=&#8221;default&#8221; column_direction_phone=&#8221;default&#8221; scene_position=&#8221;center&#8221; text_color=&#8221;dark&#8221; text_align=&#8221;left&#8221; row_border_radius=&#8221;none&#8221; row_border_radius_applies=&#8221;bg&#8221; overflow=&#8221;visible&#8221; overlay_strength=&#8221;0.3&#8243; gradient_direction=&#8221;left_to_right&#8221; shape_divider_position=&#8221;bottom&#8221; bg_image_animation=&#8221;none&#8221;][vc_column column_padding=&#8221;no-extra-padding&#8221; column_padding_tablet=&#8221;inherit&#8221; column_padding_phone=&#8221;inherit&#8221; column_padding_position=&#8221;all&#8221; 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